(1) Drugs can affect transmitters in different ways. They can affect the production of the transmitter by preventing synthesis, blacking the axonal transport, or messing with storage transmitters. Thi
Drugs can affect transmitters in different ways. They can affect the production of the transmitter by preventing synthesis, blacking the axonal transport, or messing with storage transmitters. This affects the behavior of a person. The second affects the release of transmitters. This can stop the synaptic nerve conduction and alter the release of synaptic transmitters. It can also cause the drugs to compete for receptors and prevent releases. This can shut down the transmission or act as transmitting but really not. The third alteration could be on the transmitter clearance. This can inactivate the reuptake and block pre and postsynaptic cells. Often times we can see this effect more with drug intake rather than food. This can cause slurring, slow muscle movement, behavior changes, and other effects that may not completely alter our bodies.
Different drugs can alter neurotransmission in different ways. Alcohol, nicotine, heroin, can put the dopamine neurons into and excited state, producing more action potential electric signals and sending more dopamine into the synapse. Some drugs also activate the receiving neuron receptors, and some block them. Caffeine, normally blocks some neurotransmitters called adenosine from attaching or binding to it’s receptors, so a person won’t feel tired or sedated because the caffeine blocked it. Cocaine, changes the way a neurotransmitter is removed from the synaptic area, it blocks the reuptake pump for dopamine, that normally removes dopamine from the synapse. This makes the synapse area filled up with dopamine, which causes the person to feel good or euphoric. THC from marijuana and morphine both activate some receptors and bind to them.
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